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Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins

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NIAID Data Ecosystem2026-04-25 收录
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We used RNA-seq to measure transcript levels in human cells with the PUM1 and PUM2 proteins knocked down; by analyzing the differences in transcript abundances between those conditions, we were able to identify 927 targets showing significant changes in the presence of the PUM knockdown. Overall design: Comparative expression profiling via RNA seq between cells undergoing shRNA-mediated PUM knockdown and cells treated with a non-target control

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2019-09-23
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