Crystal structure of human anaplastic lymphoma kinase in complex with a piperidine-carboxamide inhibitor
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Crystal structure of human anaplastic lymphoma kinase in complex with a piperidine-carboxamide inhibitor Descriptor: (3S)-N-(4-methylbenzyl)-1-{2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}piperidine-3-carboxamide, ALK tyrosine kinase receptor Authors: Whittington, D.A, Epstein, L.F, Chen, H. Deposit date: 2012-01-17 Release date: 2012-02-08 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.03 Å) Cite: Rapid development of piperidine carboxamides as potent and selective anaplastic lymphoma kinase inhibitors. J.Med.Chem., 55, 2012
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2012-01-17
