Salivary Microbiome in Patients with Schizophrenia

We used 16S rRNA gene sequencing to investigate the salivary microbiome in patients with first-episode schizophrenia, individuals at clinical high risk for psychosis and healthy controls. This study provides the first evidence of the identity, quantity and functions of microbes in the saliva of patients with schizophrenia and provides a unique framework for understanding oral microbial dysbiosis in this disease.