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Summary of derived SRT2104 pharmacokinetic parameters by dose level.

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1Median is presented for tmax. 2Geometric mean is presented for AUC0-∞. Abbreviations: Cmax = maximum plasma concentration. tmax = time of peak plasma concentration. AUC0-t = area under the plasma concentration-time curve from zero to the time of the last measurable concentration. AUC0-∞ = area under the plasma concentration-time curve from zero to infinity. t1/2 = half life. CL/F = clearance.

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2012-12-20
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