Exercise and Sestrin mediate speed and lysosomal activity in Drosophila by partially overlapping mechanisms-source data
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Source data, Figures 1-7
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2021-08-19
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PA up-regulates the KEGG pathway ‘Lysosome’ in cultured PTECs. PA up-regulates the KEGG pathway ‘Lysosome’ in cultured PTECs
Obesity is a major risk factor for end-stage kidney disease. We previously found that lysosomal dysfunction and impaired autophagic flux contribute to lipotoxicity in experimental and human obesity-re
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A lysosomal surveillance response to stress extends healthspan [Exp1]. A lysosomal surveillance response to stress extends healthspan [Exp1]
Lysosomes are cytoplasmic organelles central for the degradation of macromolecules to maintain cellular homeostasis and health. However, how lysosomal activity can be boosted to counteract aging and a
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Immunoblots for data in Qin et al, 2025, SARS-CoV-2 enhances lysosomal exocytosis efficiency and deacidifies lysosomes to facilitate viral release
Page 2 presents the original, unedited images to generate Figure S1E. Effects of CID1067700 on intracellular LAMP1 in SARS-CoV-2-trVLP-infected cells (8–14 h pi) by western blot. DMSO treatment served
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A Drosophila toolkit for HA-tagged proteins unveils a block in autophagy flux in the last instar larval fat body. A Drosophila toolkit for HA-tagged proteins unveils a block in autophagy flux in the last instar larval fat body
The lysosomal function is down-regulated in the white prepupal fat body, resulting in the enlargement of lysosomes in the tissue. The enlargement is blocked by the forced activation of lysosomes by th
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A lysosomal surveillance response to stress extends healthspan [Exp3]
Lysosomes are cytoplasmic organelles central for the degradation of macromolecules to maintain cellular homeostasis and health. However, how lysosomal activity can be boosted to counteract aging and a
NIAID Data Ecosystem20
