Tlr4

ENCODES a protein that exhibits lipopolysaccharide binding (ortholog); phosphatidylinositol 3-kinase binding (ortholog); INVOLVED IN activation of innate immune response (ortholog); astrocyte development (ortholog); B cell proliferation (ortholog); PARTICIPATES IN titanium dioxide nanoparticle response pathway; Toll-like receptor signaling pathway; ASSOCIATED WITH Acanthamoeba Keratitis (ortholog); Acne Conglobata (ortholog); Acute Coronary Syndrome (ortholog); FOUND IN cell surface (ortholog); endosome membrane (ortholog); plasma membrane (ortholog)

编码一种具有脂多糖结合（同源）特性、磷脂酰肌醇3激酶结合（同源）特性、参与先天免疫反应激活（同源）、星形胶质细胞发育（同源）、B细胞增殖（同源）的蛋白；参与二氧化钛纳米粒子反应通路、Toll样受体信号通路；与棘阿米巴角膜炎（同源）、痤疮性聚合性痤疮（同源）、急性冠脉综合征（同源）相关；存在于细胞表面（同源）、内质网膜（同源）、质膜（同源）。