Establishment of human teeth relies on coordinated formation of dentin-pulp complex for nurturing and periodontal tissues for anchoring in alveolar bone. The exact cell origin of dentin-pulp complex a
We show that loss of Arid1a impairs the differentiation-associated cell cycle arrest of tooth root progenitors through Hh signaling regulation, leading to shortened roots. Our data suggest that Plagl1
AbstractThe mammalian dentition is uniquely characterized by a combination of precise occlusion, permanent adult teeth, and a unique tooth attachment system. Unlike the ankylosed teeth in most reptile