five

Crystal structure of BRD2(BD2) W370F mutant with ligand 28 bound

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Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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Crystal structure of BRD2(BD2) W370F mutant with ligand 28 bound Descriptor: Bromodomain-containing protein 2, GLYCEROL, methyl [(4S)-6-(1H-indol-4-yl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]acetate Authors: Tallant, C, Baud, M, Lin-Shiao, E, Chirgadze, D.Y, Ciulli, A. Deposit date: 2015-08-26 Release date: 2015-11-11 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.5 Å) Cite: New Synthetic Routes to Triazolo-benzodiazepine Analogues: Expanding the Scope of the Bump-and-Hole Approach for Selective Bromo and Extra-Terminal (BET) Bromodomain Inhibition. J.Med.Chem., 59, 2016
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2015-08-26
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