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Cagrilintide and retatrutide combination therapy enhances weight loss and metabolic outcomes in obese rats

ChEBI2026-07-20 更新2026-07-31 收录

肥胖症药物研究

代谢疾病动物模型

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-16695 数据链接链接失效反馈

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资源简介：

Cagrilintide and retatrutide combination therapy enhances weight loss and metabolic outcomes in obese rats

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创建时间：

2026-07-20

TGR5受体

代谢疾病动物模型

Takeda G protein-coupled receptor 5 (TGR5) is a promising target for treating metabolic syndrome and inflammatory diseases. Herein, we identified a new series of betulinic acid derivatives as potent T

NIAID Data Ecosystem80

Transcription profiling by array of adipose samples from LDLR-/- mice to study response to anti-diabetic drug and dietary lifestyle interventions

糖尿病前期干预

代谢疾病动物模型

Lean male mice were fed a high fat diet (HFD, lard 24% w/w) for 16 weeks. At 9 weeks, when all hallmarks of prediabetes were established, groups of mice were treated with drug (rosiglitazone, pioglita

NIAID Data Ecosystem40

Correlations between liver TG content and long chain fatty acyl CoA with clinical and biochemical markers in baboons.

代谢疾病动物模型

脂质代谢

Obesity and insulin resistance is significantly correlated with higher liver TG content, and deleterious long chain fatty acyl CoA profile in baboons. NEFA = non-esterified fatty acids; FPI = fasting

Figshare2015-12-02 更新30

Correlation between Serum Uric Acid (SUA) and inflammatory markers in MCD and Obese Zucker rats.

代谢疾病动物模型

尿酸炎症相关性

Correlation between Serum Uric Acid (SUA) and inflammatory markers in MCD and Obese Zucker rats.

NIAID Data Ecosystem60

Efffect of a high fructose diet on gene expression in vervet monkey livers.

营养基因组学

代谢疾病动物模型

High-throughput profiling of gene expression in the livers of vervet monkeys fed a high fructose diet or chow diet. Analysis of differentially expressed genes revealed sirtuin signaling and a network

NIAID Data Ecosystem40

Cagrilintide and retatrutide combination therapy enhances weight loss and metabolic outcomes in obese rats

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