Differentiation of lncRNAs expression during the polarization macrophages. Differentiation of lncRNAs expression during the polarization macrophages

To determine lncRNAs transcribed during the polarization of macrophages, we have employed whole genome microarray expression profiling as a discovery platform to identify lncRNAs expression in mouse primary bone marrow derived macrophages (BMDMs) treated with M1 (lipopolysaccharide, LPS) and M2 (IL-4) stimulators. Overall design: The changed lncRNA expression in mouse BMDMs untreated (M/Ctrl) , or treated with LPS 6hours, IL-4 24 hours, respectively. Three independent experiments were performed at each treat (M, LPS, IL-4).