ABSTRACT Substances with cytotoxic activity present in vaccines against the foot-and-mouth disease may interfere with methods used to detect residual live virus in the product or cause undesirable pos
aCC50∶50% cytotoxic concentration (µg/ml). bMNTD: maximum non- toxic dose based on MTT and Neutral Red assays. cPhaeophyta = Brown seaweeds; Rhodophyta = Red seaweeds; Chlorophyta = Green seaweeds.
NIH3T3 mouse fibroblasts were seeded in a 48 well plate (20,000 cells/400 µl per well) and treated with 0.5 µM MunI (48 h) or 0.05 µM MunI (72 h) alone or in complex with SAINT-PhD. Forty-eight and 72