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Next-generation mRNA sequencing of MKL-1 Merkel cell carcinoma cells expressing wild-type or mutant YAP or TAZ

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE189054
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The overarching goal of this study was to characterize TEAD-dependent transcriptional effects of YAP and TAZ in Merkel cell carcinoma cells. To that end, transcriptional profiling was performed on MKL-1 cells induced to express GFP, wild-type YAP or TAZ, or YAP S94A or TAZ F52A for 3 days. MKL-1 cells with doxycycline-inducible GFP, YAP, TAZ, YAP S94A, or TAZ F52A were treated in triplicate with 2 µg/mL doxycycline for 3 days. 15 samples are analyzed.
创建时间:
2023-03-03
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