Halocyclization of Unsaturated Guanidines Mediated by Koser’s Reagent and Lithium Halides
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The synthesis of halogenated cyclic guanidines through iodine(III)-mediated umpolung of halide salts is described. Cyclic guanidines of various sizes can be obtained with generally excellent regioselectivities through either a chloro- or a bromocyclization, using Koser’s reagent and the corresponding lithium salt.
创建时间：
2016-02-12
