Zwitterionic N2O2‑Type Protonated Dipyrrin Bearing a Phosphate Anionic Moiety as a pH-Responsive Fluorescence Indicator
收藏Figshare2016-02-15 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Zwitterionic_N_sub_2_sub_O_sub_2_sub_Type_Protonated_Dipyrrin_Bearing_a_Phosphate_Anionic_Moiety_as_a_pH_Responsive_Fluorescence_Indicator/2204986
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Zwitterionic protonated-dipyrrin 1 bearing a phosphate unit was synthesized from the N2O2-type tetradentate dipyrrin ligand. Compound 1 is in equilibrium with the deprotonated form 1′ with a pKa value of 5.8. Compound 1 exhibited a pH-responsive fluorescence under physiological conditions; the fluorescence intensity increased in aqueous media as the pH increased. In living cells, 1 also exhibited emission responsive to pH. Thus, 1 should be applicable as a pH probe for detecting tumor cells.
创建时间：
2016-02-15
