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Epigenetic and metabolic reprogramming by HDAC inhibition targets NRF2-active tumors [RNA-Seq]

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE220837
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To investigate the NRF2-specific cytotoxic effects of HDAC inhibition, we assessed gene expression in the context of control and NRF2-overexpressing mouse LUAD cells upon HDAC inhibition. Comparative gene expression profiling analysis of RNA-seq data of KP1 EV and NRF2 cells treated with DMSO or Romidepsin. 3 biological replicates per condition are included
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2024-02-15
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