Statistically significant correlations between AS3MT haplotype and DNA methylation in either Argentina or in Bangladesh, as well as descriptions of the DNA methylation sites.
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*According to NCBI Ref. Sequence: NC_000010.10, H sapiens chromosome 10, GRCh37.p5 Primary Assembly [42].†Situated in a CpG island, shore, or shelf according to Emboss CpGPlot [41].‡Enhancer elements were defined according to Illumina’s annotations (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GPL13534).§According to http://www.rforge.net/IMA/snpsites.txt. The numbers in parentheses indicate the distance of the SNP from the CpG site.¶r = Pearson product-moment correlation coefficient.∥Beta (β)-values represent the fraction of methylation and hence range from 0 (unmethylated) to 1 (methylated).Abbreviations: FDR; False Discovery Rate, SNP = Single nucleotide polymorphism.
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2015-12-02



