Association between different timing of ultrasonographic surveillance and the risk of mortality following hepatocellular carcinoma diagnosis among patients with viral hepatitis: Cox proportional-hazards regression models, with survival times uncorrected and corrected for lead time bias.

*Adjusted for: age at HCC diagnosis; sex; rural residence; income quintile; Charlson-Deyo Comorbidity Index; diabetes diagnosis; indicators of severe liver disease: No alcoholic liver disease (ALD)+no cirrhosis; No ALD+Cirrhosis only; No ALD+Decompensated cirrhosis; ALD+No cirrhosis; ALD+Cirrhosis; ALD+Decompensated cirrhosis; Non-alcoholic fatty liver disease (NAFLD)+Cirrhosis; and index year of hepatocellular carcinoma (HCC) diagnosis.
†All covariates, including receipt of HCC curative treatment (i.e., surgical resection, liver transplantation, or radiofrequency ablation). Variables modeled as time-dependent covariate include: Charlson-Deyo Comorbidity Index; diabetes diagnosis; and HCC curative treatment.
Association between different timing of ultrasonographic surveillance and the risk of mortality following hepatocellular carcinoma diagnosis among patients with viral hepatitis: Cox proportional-hazards regression models, with survival times uncorrected and corrected for lead time bias.