Summary statistics for Polygenic and developmental profiles of autism differ by age at diagnosis

<b>Summary statistics for Zhang et al., Nature, 2025.</b><br><br>Earlier_diagnosed_autism.txt: GWAS generated from a genomicSEM model representing earlier diagnosed autism<br>Later_diagnosed_autism.txt: GWAS generated from a genomicSEM model representing later diagnosed autism<br>SPARK_agediagnosis_meta.txt: GWAS of age at diagnosis from SPARKFor all datasets, A1 = effect allele, A2 = non-effect allele. Allele frequencies and Effects are with reference to A1.<br><br>For the two SEM-derived GWAS, N_effective provides the effective sample calculated as the sum of the factor-loading weighted effective sample size for each GWAS included in the factor. <br><br><br><b>Terms of use</b><br><br>Investigators acknowledge that these data are provided on an “as-is” basis, without warranty of any type, expressed or implied, including but not limited to any warranty as to their performance, merchantability, or fitness for any particular purpose;<br>Investigators will not cross-post these data or make them available elsewhere – this website is the definitive source for these data;Investigators will never attempt to identify any participant who contributed to these data;Investigators will only use these data for scientific research only'Investigators are responsible for ensuring that their use of these data is always in compliance with all local, state, national, and institutional regulations/policies regarding human subjects, genetics research, and these data – for example, these links are for the US and UK standards;Investigators may not use these data to develop any type of risk or predictive test for an unborn individual;Investigators will cite the appropriate publication in any presentations, publications, or communications or publications arising from use of these data; and