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The dynamic, combinatorial cis-regulatory lexicon of epidermal differentiation [PAS-seq]. The dynamic, combinatorial cis-regulatory lexicon of epidermal differentiation [PAS-seq]

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NIAID Data Ecosystem2026-03-12 收录
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A deep-learning framework interprets multi-omic data across epidermal differentiation, identifying cooperative DNA sequence rules that regulate gene modules. Massively parallel reporter analysis validates temporal dynamics and cis-regulatory logic. Overall design: PAS-seq performed on days 0-6 of keratinocyte differentiation, every 12 hours (https://www.encodeproject.org/treatment-time-series/ENCSR057HZF/).

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2021-08-03
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