Table S8 from Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations
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Results of LentiMutate on KRAS-G12C cDNA and AMG 510 in the H358 cell line. Values shown are the averages of two biological replicates. The fold enrichment of "All nucleotides" is the sum of substitution rates for all nucleotides in the with doxycycline replicates divided by the sum of substitution rates for all nucleotides without doxycycline (parental) at one nucleotide position. Nucleotide w/ max error refers to the highest substitution rate for a single nucleotide at one nucleotide position.
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2021-09-15
