Greenness assessment of microextractiontechniques in therapeutic drug monitoring: supplementary materials

Aim: In this study, we evaluated the greenness and whiteness scores for microextraction techniques used
in therapeutic drug monitoring. Additionally, the cons and pros of each evaluated method and their
impacts on the provided scores are also discussed. Materials & methods: The Analytical Greenness Sample
Preparation metric tool and white analytical chemistry principles are used for related published works
(2007–2023). Results & conclusion: This study provided valuable insights for developing methods based
on microextraction techniques with a balance in greenness and whiteness areas. Some methods based
on a specific technique recorded higher scores, making them suitable candidates as green analytical
approaches, and some others achieved high scores both in green and white areas with a satisfactory
balance between principles.