Route for the Generation of Trifluoromethyl-Substituted Pyrrplo[3,2‑<i>c</i>]quinolines
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资源简介：
Generation of trifluoromethyl-substituted pyrrolo[3,2-c]quinolines via a copper(II)-catalyzed tandem reaction of N-(σ-iodoaryl)alkynylimines with 2-isocyanoacetates is reported. The process involves a [3 + 2] cycloaddition and intramolecular C–C bond coupling, leading to the fluorine-containing N-heterocycles under mild conditions with high efficiency.
创建时间：
2016-10-03
