Piezo1 activates specific pathways and aggravates psoriasis through two pathways

NIAID Data Ecosystem2026-05-10 收录

银屑病分子机制

PI3K/AKT信号通路

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https://www.ncbi.nlm.nih.gov/sra/SRP618373 数据链接链接失效反馈

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资源简介：

Piezo1 Aggravates Psoriasis by Promoting Macrophage M1 Polarization and Suppressing Autophagy via PI3K/AKT Pathway Activation

创建时间：

2025-09-11

Decrease in Rnase HII and accumulation of lncRNAs/DNA hybrids: a causal implication in psoriasis?

银屑病分子机制

DNA/RNA杂交体

Long functional non-coding RNAs (lncRNAs) have been in the limelight in aging research because short telomeres are associated with higher levels of TERRA (Telomeric Repeat containing RNA). The genomic

NIAID Data Ecosystem80

Data_Sheet_3_Regulation of COL1A2, AKT3 genes, and related signaling pathway in the pathology of congenital talipes equinovarus.ZIP

先天性马蹄内翻足

PI3K/AKT信号通路

Congenital talipes equinovarus (CTEV) is one of the most common congenital limb defects in children, which is a multifactorial and complex disease that associates with many unknown genetic, social-dem

NIAID Data Ecosystem30

SHP2 Blockade Sensitizes Metastatic Triple Negative Breast Cancer to PI3K Inhibition

三阴性乳腺癌药物敏感性

PI3K/AKT信号通路

Next Generation Sequencing was applied to investigate the effects of PI3K inhibition and/or SHP2 inhibition on the mouse mammary carcinoma 4T1. RNA-Seq in 4 different treatment conditions to investiga

NIAID Data Ecosystem10

JNK1 Signaling Downstream of the EGFR Pathway Contributes to Imiquimod-induced Skin Inflammation (RNA-seq)

银屑病分子机制

炎症信号通路

c-Jun N-terminal protein kinase 1 (JNK1) is involved in multiple biological processes but its implication in inflammatory skin diseases is still poorly defined. Herein, we studied the role of JNK1 in

NIAID Data Ecosystem50

Epigenetic silencing of JAM3 promoted progression in serous ovarian carcinoma through PI3K/AKT pathway

卵巢癌分子机制

PI3K/AKT信号通路

Junctional adhesion molecule 3 (JAM3) is frequently epigenetically silenced in cancers, but its functional role and regulatory mechanisms in serous ovarian carcinoma (SOC) remained poorly defined. Thi

NIAID Data Ecosystem20

Piezo1 activates specific pathways and aggravates psoriasis through two pathways

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