Structure of KPC-2 bound to QPX7728 at 1.30 A
收藏Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Structure of KPC-2 bound to QPX7728 at 1.30 A Descriptor: (1aR,7bS)-5-fluoro-2-hydroxy-1,1a,2,7b-tetrahydrocyclopropa[c][1,2]benzoxaborinine-4-carboxylic acid, (1~{a}~{R},7~{b}~{S})-5-fluoranyl-2,2-bis(oxidanyl)-1~{a},7~{b}-dihydro-1~{H}-cyclopropa[c][1,2]benzoxaborinine-4-carboxylic acid, Carbapenem-hydrolyzing beta-lactamase KPC, ... Authors: Pemberton, O.A, Chen, Y. Deposit date: 2019-11-20 Release date: 2020-03-25 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Discovery of Cyclic Boronic Acid QPX7728, an Ultrabroad-Spectrum Inhibitor of Serine and Metallo-beta-lactamases. J.Med.Chem., 63, 2020
创建时间:
2019-11-20



