Regression models: Association of high clinical threshold [9] levels of serum IgG to selected periodontal species and incident AD.

Model 1: bivariate association with single periodontal antibody.
Model 2: controlled for age at phlebotomy (baseline).
Model 3: Model 2, also controlled for APOE status, gender, and education.
Model 4: Model 3, also controlled for hypertension, smoking, stroke, and diabetes mellitus.
*Models shown using pseudolikelihood estimator, robust variance estimator, and weight of cases (1), controls (10) [most conservative method].
Models highlighted in bold indicate p<0.05. HR: Hazard ratio.
Regression models: Association of high clinical threshold [9] levels of serum IgG to selected periodontal species and incident AD.