Investigating gene expression changes in a mouse model of Alzheimer's disease upon sustained TREM2 stabilization at single cell resolution. Mus musculus

NIAID Data Ecosystem2026-03-12 收录

阿尔茨海默病分子机制

单细胞转录组学

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA714499 数据链接链接失效反馈

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资源简介：

To investigate the effect of sustained Trem2 stabilization (using IPD-substitution) on microglia during progression of Ab pathology in a mouse model of Alzheimer's disease, we performed scRNAseq of mouse cortical region from 4 different genotypes (WT, Trem2-IPD, APP23xPS45 and APP23xPS45xIPD) at 3 and 7 months of age.

创建时间：

2021-03-15