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crystal structure of human Cytochrome P450 8B1 in complex with a C12-Pyridine Containing Steroid

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Protein Data Bank Japan2026-03-04 更新2026-04-19 收录
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crystal structure of human Cytochrome P450 8B1 in complex with a C12-Pyridine Containing Steroid Descriptor: 12-(pyridin-3-yl)-8alpha,10alpha,13alpha,14beta-androsta-4,11-diene-3,17-dione, 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE Authors: Liu, J, Scott, E.E. Deposit date: 2022-10-03 Release date: 2023-08-02 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Pyridine-containing substrate analogs are restricted from accessing the human cytochrome P450 8B1 active site by tryptophan 281. J.Biol.Chem., 299, 2023
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2022-10-03
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