A chimeric haemagglutinin-based universal influenza virus vaccine boosts human cellular immune responses directed towards the conserved haemagglutinin stalk domain and the viral nucleoprotein.
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The authors sought to determine whether the vaccines utilized in the observer-blind, randomized placebo-controlled phase I trial (NCT03300050) could, in addition to elicit durable HA stalk specific antibodies, boost T-cell responses against HA stalk, and nucleoprotein (NP).
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ImmPort创建时间:
2024-04-25



