WP5475 - Hallmark of cancer: sustaining proliferative signaling - Homo sapiens
收藏NIAID Data Ecosystem2026-05-02 收录
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资源简介：
Proliferative signalling in cancer cells
应用场景：
创建时间：
2025-04-17
相关数据集
Velcrin-induced selective cleavage of tRNALeu(TAA) by SLFN12 causes cancer cell death [RNA-Seq]. Velcrin-induced selective cleavage of tRNALeu(TAA) by SLFN12 causes cancer cell death [RNA-Seq]
Velcrin compounds kill cancer cells expressing high levels of phosphodiesterase 3A (PDE3A) and Schlafen family member 12 (SLFN12) by inducing complex formation between these two proteins, but the mech
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DataSheet1_GM-CSF-miRNA-Jak2/Stat3 Signaling Mediates Chemotherapy-Induced Cancer Cell Stemness in Gastric Cancer.pdf
Chemotherapy serves as the first choice in clinic to treat advanced gastric cancer. However, emerging evidence indicated the induction of drug resistance and cancer stem cells occasionally by chemothe
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CD95L mRNA is toxic to cells [SmallRNA_CD95L.50hrs.Drosha_ko]
>80% of a large number of tested siRNAs and shRNAs targeting CD95 or CD95 ligand (CD95L) induce a form of cell death that is characterized by the simultaneous activation of multiple death pathways and
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Oncogene-dependent regulation of tumor cells via stromal reciprocal signalling
Cancer is a heterocellular disease composed of tumor cells and stromal cells. Although stromal cells are known to regulate cancer progression, oncogene-dependent signalling through heterocellular canc
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RasV12 blocks DNA synthesis and DNA damage response
Transcriptional profile of RasV12 expressing cells shows an upregulation of RTK signalling genes and a downregulation in genes involved in DNA sintesis and DNA damage response. mRNA expression profile
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