Additional file 1 of Characterizing Human Oxidative, Anabolic and Glycolytic Metabolism in Athletes with Extreme Physiologies

Supplementary material 1. Supplementary Table S1. Phenotypic traits (health, training and dietary supplement intake) measured in our study groups for each individual. Supplementary Table S2. Characteristics of 1020 quantified metabolites including metabolite missingness and coefficient of variation (cv) before and after batch correction. Supplementary Table S3. Module overview for the resulting six modules (only metabolites that overlap in baseline and post-exercise) including metabolite superpathways, subpathways, module membership and significance (referring to baseline metabolite levels) of the module membership. Supplementary Table S4. Module associations. (A) Results of a linear model to associate metabolite modules to phenotypic traits. Nominally significant associations (directionality and strength shown by beta estimates) are bolded (p 1 or < − 1 and with a p-value < 5.8E−05 (corrected for multiple testing (Bonferroni)) are additionally labelled.