Iron-Catalyzed Oxidation Intermediates Captured in A DNA Repair Dioxygenase

NIAID Data Ecosystem2026-05-02 收录

酶催化机制

DNA损伤修复

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https://www.rcsb.org/structure/3O1R 数据链接链接失效反馈

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Iron-Catalyzed Oxidation Intermediates Captured in A DNA Repair Dioxygenase

创建时间：

2024-10-30

Discovery of Isaindigotone Derivatives as Novel Bloom’s Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair

DNA损伤修复

抗癌药物设计

Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

NIAID Data Ecosystem40

SNAPSHOTS OF ENZYMATIC BAEYER-VILLIGER CATALYSIS: OXYGEN ACTIVATION AND INTERMEDIATE STABILIZATION: COMPLEX WITH NADP and MES

Baeyer-Villiger氧化反应

酶催化机制

SNAPSHOTS OF ENZYMATIC BAEYER-VILLIGER CATALYSIS: OXYGEN ACTIVATION AND INTERMEDIATE STABILIZATION: COMPLEX WITH NADP and MES

NIAID Data Ecosystem10

Structure of Gan1D-E170Q, a catalytic mutant of a putative 6-phospho-beta-galactosidase from Geobacillus stearothermophilus

蛋白质结构解析

酶催化机制

Structure of Gan1D-E170Q, a catalytic mutant of a putative 6-phospho-beta-galactosidase from Geobacillus stearothermophilus

NIAID Data Ecosystem10

MOLYBDOPTERIN SYNTHASE (MOAD/MOAE)

钼蝶呤合酶

酶催化机制

MOLYBDOPTERIN SYNTHASE (MOAD/MOAE)

NIAID Data Ecosystem10

E. coli DHFR complex with NADP+ and folate: EF-X off model by Laue diffraction (no electric field)

蛋白质结构解析

酶催化机制

E. coli DHFR complex with NADP+ and folate: EF-X off model by Laue diffraction (no electric field) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalt

Protein Data Bank Japan2024-10-09 更新10

Iron-Catalyzed Oxidation Intermediates Captured in A DNA Repair Dioxygenase

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