Crystal structure of cAMP-dependent protein kinase A (CHO PKA) in complex with 4-(trifluoromethyl)benzoic acid
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Crystal structure of cAMP-dependent protein kinase A (CHO PKA) in complex with 4-(trifluoromethyl)benzoic acid Descriptor: 4-(trifluoromethyl)benzoic acid, DIMETHYL SULFOXIDE, METHANOL, ... Authors: Oebbeke, M, Siefker, C, Heine, A, Klebe, G. Deposit date: 2019-09-02 Release date: 2020-09-30 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.37 Å) Cite: Fragment Binding to Kinase Hinge: If Charge Distribution and Local pK a Shifts Mislead Popular Bioisosterism Concepts. Angew.Chem.Int.Ed.Engl., 60, 2021
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2019-09-02
