Human Pleckstrin Homology Domain Interacting Protein (Phip); A Target Enabling Package
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SGC Oxford has expressed, purified and crystallized the second bromodomain of PHIP as part of the probe programme. Fragment screening and X-ray crystallography identified binders, some of which optimised to uM affinity. However, molecules with probe properties were not obtained. Consequently it has been decided to put the information generated into the public domain.
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Zenodo创建时间：
2018-04-17
