PRMT5 complex bound to covalent PBM inhibitor BRD6711
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PRMT5 complex bound to covalent PBM inhibitor BRD6711 Descriptor: 2-(5-chloro-6-oxopyridazin-1(6H)-yl)-N-(4-methyl-3-sulfamoylphenyl)acetamide, CHLORIDE ION, GLYCEROL, ... Authors: McMillan, B.J, McKinney, D.C. Deposit date: 2019-11-19 Release date: 2020-11-25 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction. J.Med.Chem., 64, 2021
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2019-11-19
