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Recombinant humant thrombomodulin treatment against endotoxemia-induced acute respiratory distress syndrome (ARDS).

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NIAID Data Ecosystem2026-03-11 收录
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We made LPS induced ARDS model mice, and determined the effect of recombinant human thrombomodulin against ARDS. Following 16-h starvation, mice were intraperitoneally injected with LPS (20 mg/kg; MilliporeSigma, Burlington, MA), and in some assays, with saline or recombinant human thrombomodulin (rhTM; Asahi Kasei Pharma Corporation, Tokyo, Japan) at 3 and 24 h post-LPS injection. Total RNA was extracted from mouse lung 30h after LPS injection.

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2020-06-09
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