Integrative Multiomics Analysis Reveals Association of Gut Microbiota and its Metabolites With Susceptibility to Keloids

Keloid scarring is a fibroproliferative disease of the skin. Owing to the poorly understood pathogenesis of keloids and their high recurrence rate, the efficacy of keloid treatment remains unsatisfactory, particularly in patients susceptible to multiple keloids. In this study, in an effort to explain the pathogenesis of multiple keloids, we aimed to explore the potential correlation between the gut microbiome and multiple keloids by conducting fecal metagenomics.