Additional file 4 of Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles

Additional file 4: Supplementary Table 1. ASC features. Details of culture conditions (CTRL, Osteoinduction and Adipoinduction) and performed assays are reported. Supplementary Table 2. Functional enriched processes identified with STRING through OA-related keywords (Chondro-, Metabol-,Catabol-, Inflamm- and Matrix). GO: Gene ontology identifier. Supplementary Table 3.Quantification of OA-related factors in ASC-CM (n = 3) expressed as mean ± SD. Details of the biological processes in which each factors is involved, according to Supplementary Table 2, are also provided. Supplementary Table 4. Principal Component Analysis (PCA) details by XLSTAT software. Number of factors analyzed for each OA-related keyword are reported in brackets. Supplementary Table 5. nLC-MS/MS quantification of OA-related factors in ASC-CM and ASC-EV (n = 3). Factors significantly different between CM and EV samples are in bold. Proteins more abundant in EV that in CM are highlighted in gray.