Metabolomics dataset associated with: NCAPG reprograms glycolytic and lipid metabolism by sustaining glycerophospholipid flux in small-cell lung cancer

This dataset contains raw LC-MS metabolomics data generated for the study: "NCAPG reprograms glycolytic and lipid metabolism by sustaining glycerophospholipid flux in small-cell lung cancer". Untargeted metabolomic profiling was performed on 46 surgically resected small-cell lung cancer (SCLC) tissues, 39 paired non-tumorous lung tissues, and corresponding serum samples. Data were acquired in both positive and negative ionization modes using LC-MS. The dataset includes raw mass spectrometry files and processed metabolomic results used for pathway enrichment, PCA, PLS-DA, volcano plot analysis, and differential metabolite identification. The study identified extensive metabolic reprogramming involving glycolysis, glycerophospholipid metabolism, and oxidative phosphorylation in small-cell lung cancer.