Hypoxia plays a key pathogenic role in the outcome of many pathologic conditions. To elucidate how organisms successfully adapt to hypoxia, a population of Drosophila melanogaster was generated, throu
Enhancers provide critical information directing cell-type specific transcriptional programs, regulated by binding of signal-dependent transcription factors and their associated cofactors. Here we rep
RNA-seq was used to generate an extensive map of the Drosophila melanogaster transcriptome by broad sampling of 10 developmental stages. In total, 142.2 million uniquely mapped 64-100bp paired-end re
This study addresses the impact of reduced expression of the drosophila orthologues of the human Spinal Muscular Atrophy (SMN1) and Amyotrophic Lateral Sclerosis (FUS and TARDBP) disease genes on the