Aggregatibacter actinomycetemcomitans RhAA1 Genome sequencing and assembly. Aggregatibacter actinomycetemcomitans RhAA1

A. actinomycetemcomitans is implicated in localized aggressive periodontitis (LAP), a form of periodontal disease that occurs in adolescents. Leukotoxin, a major toxin produced by this bacterium is specific only to humans and old world primates. Occurrence of periodontitis in old world and new world monkeys is ambiguous in literature, however. To gain a greater insight into the effect of A.actinomycetemcomitans on disease initiation, we have undertaken whole genome sequencing of A. actinomycetemcomitans isolates from monkeys and comparative genomic analysis to sequenced genomes from humans. The A. actinomycetemcomitans RhAA1 was isolated from buccal swabs taken from a Rhesus macaque monkey.