In vitro and in vivo growth screen data, HCC827 cells, Source data for Fig 1. Mini-library CRISPRi screen in HCC827 cells, raw data. The read counts for each sgRNA in all in vitro and in vivo (flank a

Figshare2022-09-22 更新50

Additional file 16 of CRISPR/dCAS9-mediated DNA demethylation screen identifies functional epigenetic determinants of colorectal cancer

癌症表观遗传学

功能基因组筛选

Additional file 16: Table S12. List of primers used in this study.

Figshare2023-08-24 更新40

Sphingobium chlorophenolicum Confronts the Stresses Associated with Pentachlorophenol and Four Toxic Downstream Metabolites to Utilize a Suboptimal Nutrient Source [Tn-Seq]

微生物降解基因

功能基因组筛选

Pentachlorophenol (PCP) is a highly toxic pesticide that was first introduced in the 1930s. The a-proteobacterium Sphingobium chlorophenolicum, which was isolated from PCP-contaminated sediment, has a

NIAID Data Ecosystem60

A gene silencing screen uncovers diverse tools for targeted gene repression in Arabidopsis

功能基因组筛选

表观遗传调控

DNA methylation has been utilized for target gene silencing in plants, however it’s not well-understood whether other silencing pathways can be also used to manipulate gene expression. Here we perform

NIAID Data Ecosystem40

whole genome CRISPR Screening (Brunello library) on AMO-1 cell line treated with Ceritnib

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