Semi-quantitative assessment of AAV serotype tropism in mouse brain.

Figshare2017-12-16 更新2026-04-29 收录

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https://figshare.com/articles/dataset/Semi-quantitative_assessment_of_AAV_serotype_tropism_in_mouse_brain_/5707870 数据链接链接失效反馈

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Semi-quantitative assessment of AAV serotype tropism in mouse brain.

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2017-12-16

The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner [Tn5_InVitro]. The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner [Tn5_InVitro]

基因治疗载体

表观遗传调控

Recombinant adeno-associated viral vectors (rAAVs) are among the most commonly used vehicles for in vivo based gene therapies. However, it is hard to predict which AAV capsid will provide the most rob

NIAID Data Ecosystem60

A deletion mutant in the human cytomegalovirus gene encoding IE1(491aa) is replication defective due to a failure in autoregulation.

病毒复制调控

基因治疗载体

Human cytomegalovirus (CMV) replication begins with the expression of two regulatory proteins, IE1(491aa) and IE2(579aa), produced from differentially spliced transcripts under control of the ie1/ie2

PubMed Central1996-10-15 更新30

Integrating Adenovirus–Adeno-Associated Virus Hybrid Vectors Devoid of All Viral Genes

基因治疗载体

病毒载体工程

Recently, we demonstrated that inverted repeat sequences inserted into first-generation adenovirus (Ad) vector genomes mediate precise genomic rearrangements resulting in vector genomes devoid of all

PubMed Central20

AAV8 human HEK293-produced, empty capsid

腺相关病毒载体

基因治疗载体

AAV8 human HEK293-produced, empty capsid Descriptor: Capsid protein Authors: Paulk, N.K, Poweleit, N. Deposit date: 2019-08-18 Release date: 2020-06-03 Last modified: 2024-03-20 Method: ELECTRON MICRO

Protein Data Bank Japan2024-03-20 更新40

Fab1-4 in complex with the capsid of Adeno-associated virus type 9

病毒衣壳-抗体复合物结构

基因治疗载体

Fab1-4 in complex with the capsid of Adeno-associated virus type 9 Descriptor: Capsid protein VP1, Fab1-4 heavy chain, Fab1-4 light chain Authors: Mietzsch, M, McKenna, R. Deposit date: 2024-03-25 Rel

Protein Data Bank Japan2025-06-11 更新20

Semi-quantitative assessment of AAV serotype tropism in mouse brain.

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