A focused gRNA library targetting mouse of deubiquitinating enzymes (DUBs), E2 ubiquitin conjugating enzymes and components of the NEDD8 pathway was used in mouse ES cells exposed to IR, 6-TG and PAR
Additional file 10: Table S13. HLD-specific gene deletion enhancement, not associated with ‘shift’ / growth deficiency. Data were selected for yeast-human homologs if the respective YKO/KD strains gen
A yeast mutant library containing all single mutations (substitutions, insertions and deletions) of the FCY1 promoter was assayed. Fitness in 5-FC [12 uM] was first measured using bulk competition for
