RNA-seq analysis evaluating effects of Cdk7 inhibitor THZ1 on responses of NRVM to adrenergic receptor agonist PE Overall design: NRVM mRNA profiles from four groups: 1. Vehicle; 2. PE (100 μM); 3. PE
A mouse model of bleomycin (BLM)-induced pulmonary fibrosis was established. IMRC-EVs were infused via the tracheal or intravenous route. By accurately measuring the transcripts provided by RNA-seq te
The zebrafish is rapidly emerging as a promising alternative in vivo model for the detection of drug-induced cardiovascular effects. Despite its increasing popularity, the ability of this model to inf
10x multiome data on E15.5 and E18.5 mouse lungs from ctrl, Tbx4-rtTa;Tet-Cre;Snai1f/f;Snai2f/f, Tbx4-rtTa;Tet-Cre;Yap1f/f;Wwtr1f/f and Tbx4-rtTa;Tet-Cre;Stk3f/f;Stk4f/f (Mst12) mice induced from E9.5
All the values are expressed as mean ± S.E. Heart weight divided by body weight (HW/BW), lung weight divided by body weight (LW/BW) and kidney weight divided by body weight (KW/BW) were also calculate