Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors

Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors Descriptor: 4-[[(2R,3S,4R,5R)-5-[6-amino-8-(quinolin-6-ylmethylamino)purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitri le, BAG family molecular chaperone regulator 1, Heat shock cognate 71 kDa protein Authors: Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E. Deposit date: 2009-01-26 Release date: 2009-03-17 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design J.Med.Chem., 52, 2009