Temporal changes of gene expression in bovine endometrium after parturition

To clarify the regenerative mechanism of endometrium after parturition in cows, mRNA expression profiles in bovine endometrium were investigated during postpartum period. after PVP-I treatment in cows. The differentially expressed genes in the endometrium between postpartum days 49-52 and days 99-101 were 23 genes, and they were much lower than those before postpartum days 49-52. This result suggests that endometrial regeneration after parturition is completely accomplished until postpartum days 49-52. To clarify the gene expression in bovine endometrium at different period after parturition, 4 female cows were used. The endometrial tissues were collected 4 times from the same individual. Several endometrial tissues were biopsied using uterine biopsy forceps from the uterine horns on 9-11, 29-32, 49-52, and 99-101 days after parturition.