Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis. Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis
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We show that GFP-(GR)100-expressing mice developed age-dependent neurodegeneration, brain atrophy, as well as motor and memory impairments through the accumulation of diffuse, cytoplasmic poly(GR). Overall design: We studied affects from GFP-(GR)100 in mice using RNA-seq
创建时间：
2018-04-10
