首页/数据集/Retinoid X Receptor activation reverses the age-related deficiency in myelin debris phagocytosis and enhances remyelination

Retinoid X Receptor activation reverses the age-related deficiency in myelin debris phagocytosis and enhances remyelination

ChEBI2015-11-04 更新2026-07-12 收录

髓鞘再生机制

神经退行性疾病治疗

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-66988 数据链接链接失效反馈

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Retinoid X Receptor activation reverses the age-related deficiency in myelin debris phagocytosis and enhances remyelination

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创建时间：

2015-11-04

靶向药物研发

神经退行性疾病治疗

In this paper, we applied an innovative nuclear magnetic resonance (NMR)-guided screening and ligand design approach, named focused high-throughput screening by NMR (fHTS by NMR), to derive potent, lo

Figshare2021-07-22 更新20

Transcriptome of Drosophila melanogaster third instar larval eye discs expressing GMR-Gal4>UAS-127Q and Wild type reared on normal food or food supplemented with Amalaki Rasayana (AR) or Rasa-Sindoor (RS)

神经退行性疾病治疗

转录组分析

Purpose: Feeding larvae of fly models of polyQ and other neurodegenerative disorders on AR or RS supplemented food substantially suppressed neurodegeneration. With a view to gain further insight into

NIAID Data Ecosystem20

Effect of tetracycline family of antibiotics on actin aggregation, resulting in the formation of Hirano bodies responsible for neuropathological disorders

神经退行性疾病治疗

肌动蛋白调控

Actin, an ATPase superfamily protein, regulates some vital biological functions like cell locomotion, cytokinesis, synaptic plasticity and cell signaling in higher eukaryotes, and is dependent on the

Figshare2020-01-17 更新00

Table_1_Breached Barriers: A Scoping Review of Blood-Central Nervous System Barrier Pathology in Amyotrophic Lateral Sclerosis.DOCX

ALS血脑屏障病理

神经退行性疾病治疗

IntroductionRecent studies have implicated changes in the blood-central nervous system barriers (BCNSB) in amyotrophic lateral sclerosis (ALS). The objective of this scoping review is to synthesize th

NIAID Data Ecosystem20

The Role of Fatty Acid-Binding Proteins in Microglial Docosahexaenoic Acid Uptake and Immunometabolism

神经退行性疾病治疗

小胶质细胞代谢

Inflammation in the brain, termed neuroinflammation, occurs very commonly in neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease. Neuroinflammation is bad as it can result in cell

Monash University Figshare2026-02-11 更新10

Retinoid X Receptor activation reverses the age-related deficiency in myelin debris phagocytosis and enhances remyelination

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