PIK3CA
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Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22. [provided by RefSeq, Apr 2016]
磷脂酰肌醇3激酶由一个85 kDa的调节亚基和一个110 kDa的催化亚基组成。本基因编码的蛋白质代表催化亚基,该亚基利用ATP对磷脂酰肌醇(PtdIns)、磷脂酰肌醇4磷酸(PtdIns4P)和磷脂酰肌醇(4,5)P2进行磷酸化。研究发现,该基因具有致癌性,并已被关联到宫颈癌。此外,该基因在染色体22上已定义了一个假基因。[由RefSeq提供,2016年4月]
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