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Crystal Structure of HIV-1 I50V, A71V Protease in Complex with the Protease Inhibitor Darunavir

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Protein Data Bank Japan2023-09-06 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3oxw
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Crystal Structure of HIV-1 I50V, A71V Protease in Complex with the Protease Inhibitor Darunavir Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, 1,2-ETHANEDIOL, ACETATE ION, ... Authors: Mittal, S, Bandaranayake, R.M, Schiffer, C.A. Deposit date: 2010-09-22 Release date: 2011-09-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural and thermodynamic basis of amprenavir/darunavir and atazanavir resistance in HIV-1 protease with mutations at residue 50. J.Virol., 87, 2013
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2010-09-22
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